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Viral vector manufacturing: quality attributes of rAAV used in clinical development

Recombinant Adeno-Associated Virus (rAAV) are widely used for human gene therapy, now the basis for two licensed products (for RPE65-/-, and SMA) and numerous other investigational treatments for a range of diseases including hemophilia, cystic fibrosis, muscular dystrophy & many neurological di...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biomol Tech
Main Authors: Alcudia, Javier, Wright, John Fraser
Format: Artigo
Jezik:Inglês
Izdano: Association of Biomolecular Resource Facilities 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7424966/
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