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CRISPR-Mediated Depletion of Ribosomal RNA-Derived DNA from RNA-Seq NGS Libraries

Although messenger RNA (mRNA) is the focus of much RNA research, it constitutes a relatively small fraction of total RNA in a cell. Most cellular RNA is ribosomal RNA (rRNA) and removal of this RNA is is desirable in many RNA-Seq studies in order to maximize capacity of the sequencing instrument and...

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Bibliographische Detailangaben
Veröffentlicht in:J Biomol Tech
Hauptverfasser: Siddique, Azeem, Suckow, Gaia, Head, Steve, Ordoukhanian, Phillip, Sussman, Hallie, Ramachandran, Dhanya, Homer, Nils, Bajena, Jorge, Brown, Keith, Chittur, Sridar, Knudtson, Kevin, Kermack, Justin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Association of Biomolecular Resource Facilities 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7424825/
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