Maturation of the Human Immunoglobulin Heavy Chain Repertoire With Age

B cells play a central role in adaptive immune processes, mainly through the production of antibodies. The maturation of the B cell system with age is poorly studied. We extensively investigated age-related alterations of naïve and antigen-experienced immunoglobulin heavy chain (IgH) repertoires. Th...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Ghraichy, Marie, Galson, Jacob D., Kovaltsuk, Aleksandr, von Niederhäusern, Valentin, Pachlopnik Schmid, Jana, Recher, Mike, Jauch, Annaïse J., Miho, Enkelejda, Kelly, Dominic F., Deane, Charlotte M., Trück, Johannes
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7424015/
https://ncbi.nlm.nih.gov/pubmed/32849618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01734
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