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Reduced axonal caliber and structural changes in a rat model of Fragile X syndrome with a deletion of a K-Homology domain of Fmr1

Fragile X syndrome (FXS) is a neurodevelopmental disorder that is caused by mutations in the FMR1 gene. Neuroanatomical alterations have been reported in both male and female individuals with FXS, yet the morphological underpinnings of these alterations have not been elucidated. In the current study...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Golden, Carla E. M., Yee, Yohan, Wang, Victoria X., Harony-Nicolas, Hala, Hof, Patrick R., Lerch, Jason P., Buxbaum, Joseph D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423986/
https://ncbi.nlm.nih.gov/pubmed/32788572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-020-00943-x
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