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Tubulin islands containing slowly hydrolyzable GTP analogs regulate the mechanism and kinetics of microtubule depolymerization

Dynamic instability of microtubules is characterized by stochastically alternating phases of growth and shrinkage and is hypothesized to be controlled by the conformation and nucleotide state of tubulin dimers within the microtubule lattice. Specifically, conformation changes (compression) in the tu...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bollinger, Jonathan A., Imam, Zachary I., Stevens, Mark J., Bachand, George D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423891/
https://ncbi.nlm.nih.gov/pubmed/32788644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70602-0
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