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CDK-regulated phase separation seeded by histone genes ensures precise growth and function of Histone Locus Bodies

Many membrane-less organelles form through liquid-liquid phase separation, but how their size is controlled and whether size is linked to function remain poorly understood. The Histone Locus Body (HLB) is an evolutionarily conserved nuclear body that regulates the transcription and processing of his...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Hur, Woonyung, Kemp, James P., Tarzia, Marco, Deneke, Victoria E., Marzluff, William F., Duronio, Robert J., Di Talia, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423771/
https://ncbi.nlm.nih.gov/pubmed/32579968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2020.06.003
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