Extracellular vesicle–encapsulated IL-10 as novel nanotherapeutics against ischemic AKI

Recently, extracellular vesicles (EVs) have been attracting strong research interest for use as natural drug delivery systems. We report an approach to manufacturing interleukin-10 (IL-10)–loaded EVs (IL-10(+) EVs) by engineering macrophages for treating ischemic acute kidney injury (AKI). Delivery...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Tang, Tao-Tao, Wang, Bin, Wu, Min, Li, Zuo-Lin, Feng, Ye, Cao, Jing-Yuan, Yin, Di, Liu, Hong, Tang, Ri-Ning, Crowley, Steven D., Lv, Lin-Li, Liu, Bi-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423360/
https://ncbi.nlm.nih.gov/pubmed/32851154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz0748
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