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High laboratory mouse pre-weaning mortality associated with litter overlap, advanced dam age, small and large litters

High and variable pre-weaning mortality is a persistent problem in laboratory mouse breeding. Assuming a modest 15% mortality rate across mouse strains, means that approximately 1 million more pups are produced yearly in the EU to compensate for those which die. This paper presents the first large s...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Morello, Gabriela M., Hultgren, Jan, Capas-Peneda, Sara, Wiltshire, Marc, Thomas, Aurelie, Wardle-Jones, Hannah, Brajon, Sophie, Gilbert, Colin, Olsson, I. Anna S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423063/
https://ncbi.nlm.nih.gov/pubmed/32785214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0236290
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