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Measurement of 17-Hydroxyprogesterone by LCMSMS Improves Newborn Screening for CAH Due to 21-Hydroxylase Deficiency in New Zealand

The positive predictive value of newborn screening for congenital adrenal hyperplasia due to 21-hydroxylase deficiency was <2% in New Zealand. This is despite a bloodspot second-tier immunoassay method for 17-hydroxyprogesterone measurement with an additional solvent extract step to reduce the nu...

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Bibliografiske detaljer
Udgivet i:Int J Neonatal Screen
Main Authors: de Hora, Mark R., Heather, Natasha L., Patel, Tejal, Bresnahan, Lauren G., Webster, Dianne, Hofman, Paul L.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7422986/
https://ncbi.nlm.nih.gov/pubmed/33073005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijns6010006
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