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Visualizing semipermeability of the cell membrane using a pH-responsive ratiometric AIEgen

In clinical chemotherapy, some basic drugs cannot enter the hydrophobic cell membrane because of ionization in the acidic tumor microenvironment, a phenomenon known as ion trapping. In this study, we developed a method to visualize this ion trapping phenomenon by utilizing a pH-responsive ratiometri...

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Bibliografiske detaljer
Udgivet i:Chem Sci
Main Authors: Gu, Yuan, Zhao, Zheng, Niu, Guangle, Zhang, Han, Wang, Yiming, Kwok, Ryan T. K., Lam, Jacky W. Y., Tang, Ben Zhong
Format: Artigo
Sprog:Inglês
Udgivet: Royal Society of Chemistry 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7422962/
https://ncbi.nlm.nih.gov/pubmed/32832051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc02097d
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