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Computational Approach for Rational Design of Fusion Uricase with PAS Sequences
Tumor lysis syndrome is a life-threatening condition for humans due to the lack of urate oxidase. In this study, several variants of PASylated uricase from the Aspergillus flavus species were analyzed computationally to find the appropriate fusions to solve short half-life and stability concern. The...
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| Udgivet i: | Int J Mol Cell Med |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Babol University of Medical Sciences
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7422847/ https://ncbi.nlm.nih.gov/pubmed/32832488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22088/IJMCM.BUMS.9.1.90 |
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