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Repurposing of existing FDA approved drugs for Neprilysin inhibition: An in-silico study

Neprilysin (NEP) is a neutral endopeptidase with diverse physiological roles in the body. NEP's role in degradation of diverse classes of peptides such as amyloid beta, natriuretic peptide, substance P, angiotensin, endothelins, etc., is associated with pathologies of alzheimer's, kidney a...

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Bibliografische gegevens
Gepubliceerd in:J Mol Struct
Hoofdauteurs: Sankhe, Runali, Rathi, Ekta, Manandhar, Suman, Kumar, Avinash, Pai, Sreedhara Ranganath K, Kini, Suvarna G, Kishore, Anoop
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier B.V. 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7422802/
https://ncbi.nlm.nih.gov/pubmed/32834116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molstruc.2020.129073
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