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Translational control by 5’-untranslated regions of eukaryotic mRNAs

The eukaryotic 5’ untranslated region (UTR) is critical for ribosome recruitment to the mRNA and start codon choice, and plays a major role in the control of translation efficiency and shaping the cellular proteome. The ribosomal initiation complex is assembled on the mRNA via a cap-dependent or cap...

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Bibliographic Details
Published in:Science
Main Authors: Hinnebusch, Alan G., Ivanov, Ivaylo P., Sonenberg, Nahum
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7422601/
https://ncbi.nlm.nih.gov/pubmed/27313038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aad9868
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