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The Investigation of the T-Type Calcium Channel Enhancer SAK3 in an Animal Model of TAF1 intellectual Disability Syndrome

T-type calcium channels, in the central nervous system, are involved in the pathogenesis of many neurodegenerative diseases, including TAF1 intellectual disability syndrome (TAF1 ID syndrome). Here, we evaluated the efficacy of a novel T-type Ca(2+) channel enhancer, SAK3 (ethyl 8’-methyl-2’, 4-diox...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Janakiraman, Udaiyappan, Dhanalakshmi, Chinnasamy, Yu, Jie, Moutal, Aubin, Boinon, Lisa, Fukunaga, Kohji, Khanna, Rajesh, Nelson, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7422587/
https://ncbi.nlm.nih.gov/pubmed/32622085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2020.105006
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