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Cinnamic Aldehyde Inhibits Lipopolysaccharide-Induced Chondrocyte Inflammation and Reduces Cartilage Degeneration by Blocking the Nuclear Factor-Kappa B Signaling Pathway

Osteoarthritis (OA), as one of the top 10 causes of physical disability, is characterized by inflammation of the synovial membrane and progressive destruction of the articular cartilage. Cinnamic aldehyde (CA), an α,β-unsaturated aldehyde extracted from the traditional Chinese herbal medicine cinnam...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Chen, Pu, Ruan, Anmin, Zhou, Jun, Huang, Liuwei, Zhang, Xiaozhe, Ma, Yufeng, Wang, QingFu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7419651/
https://ncbi.nlm.nih.gov/pubmed/32848721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00949
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