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USP7 Is a Master Regulator of Genome Stability

Genetic alterations, including DNA mutations and chromosomal abnormalities, are primary drivers of tumor formation and cancer progression. These alterations can endow cells with a selective growth advantage, enabling cancers to evade cell death, proliferation limits, and immune checkpoints, to metas...

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Bibliographic Details
Published in:Front Cell Dev Biol
Main Authors: Valles, Gabrielle J., Bezsonova, Irina, Woodgate, Roger, Ashton, Nicholas W.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7419626/
https://ncbi.nlm.nih.gov/pubmed/32850836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00717
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