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Epigenetics meets GPCR: inhibition of histone H3 methyltransferase (G9a) and histamine H(3) receptor for Prader–Willi Syndrome
The role of epigenetic regulation is in large parts connected to cancer, but additionally, its therapeutic claim in neurological disorders has emerged. Inhibition of histone H3 lysine N-methyltransferase, especially G9a, has been recently shown to restore candidate genes from silenced parental chrom...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7419559/ https://ncbi.nlm.nih.gov/pubmed/32782417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70523-y |
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