Inhibition of Circulating miR-194-5p Reverses Osteoporosis through Wnt5a/β-Catenin-Dependent Induction of Osteogenic Differentiation

Mesenchymal stem cells (MSCs) critically contribute to bone formation, and proper induction of osteogenic differentiation can lead to an increase in bone mass. In the present study, we reported that an increased miR-194-5p level in plasma is inversely related to the degree of bone formation in osteo...

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Bibliographic Details
Published in:Mol Ther Nucleic Acids
Main Authors: Mi, Bobin, Yan, Chenchen, Xue, Hang, Chen, Lang, Panayi, Adriana C., Hu, Liangcong, Hu, Yiqiang, Cao, Faqi, Sun, Yun, Zhou, Wu, Xiong, Yuan, Liu, Guohui
Format: Artigo
Language:Inglês
Published: American Society of Gene & Cell Therapy 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7419275/
https://ncbi.nlm.nih.gov/pubmed/32791453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.07.023
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