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Evaluation of Nivolumab for Ototoxic Effects: An Animal Study in Rats

OBJECTIVES: The aim of this study was to assess whether nivolumab is ototoxic in rats and whether this ototoxicity is dose-dependent. MATERIALS AND METHODS: Twelve rats were divided into two groups: Group 1 (control group, 6 rats, 12 ears) received intraperitoneal saline for 14 days. Group 2 (study...

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Detalhes bibliográficos
Publicado no:J Int Adv Otol
Main Authors: Güler, İsmail, Kuzucu, İhsan, Baklacı, Deniz, Kum, Rauf Oğuzhan, Uçaryılmaz, Esra Özhamam, Özcan, Müge
Formato: Artigo
Idioma:Inglês
Publicado em: The European Academy of Otology and Neurotology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7419109/
https://ncbi.nlm.nih.gov/pubmed/32510456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5152/iao.2020.7123
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