Mapping subcortical brain alterations in 22q11.2 deletion syndrome: Effects of deletion size and convergence with idiopathic neuropsychiatric illness

OBJECTIVE: 22q11.2 deletion syndrome (22q11DS) is among the strongest known genetic risk factors for schizophrenia. Prior studies report variable alterations in subcortical brain structures in 22q11DS. To better characterize subcortical alterations in 22q11DS, including modulating effects of clinica...

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Publicado no:Am J Psychiatry
Main Authors: Ching, Christopher R.K., Gutman, Boris A., Sun, Daqiang, Reina, Julio Villalon, Ragothaman, Anjanibhargavi, Isaev, Dmitry, Zavaliangos-Petropulu, Artemis, Lin, Amy, Jonas, Rachel K., Kushan, Leila, Pacheco-Hansen, Laura, Vajdi, Ariana, Forsyth, Jennifer K., Jalbrzikowski, Maria, Bakker, Geor, van Amelsvoort, Therese, Antshel, Kevin M., Fremont, Wanda, Kates, Wendy R., Campbell, Linda E., McCabe, Kathryn L., Craig, Michael C., Daly, Eileen, Gudbrandsen, Maria, Murphy, Clodagh M., Murphy, Declan G., Murphy, Kieran C., Fiksinski, Ania, Koops, Sanne, Vorstman, Jacob, Crowley, T. Blaine, Emanuel, Beverly S., Gur, Raquel E., McDonald-McGinn, Donna M., Roalf, David, Ruparel, Kosha, Schmitt, J. Eric, Zackai, Elaine H., Durdle, Courtney A., Goodrich-Hunsaker, Naomi J., Simon, Tony. J, Bassett, Anne S., Butcher, Nancy J., Chow, Eva W. C., Vila-Rodriguez, Fidel, Cunningham, Adam, Doherty, Joanne, Linden, David E., Moss, Haley, Owen, Michael J., van den Bree, Marianne, Crossley, Nicolas A., Repetto, Gabriela M., Thompson, Paul M., Bearden, Carrie E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7419015/
https://ncbi.nlm.nih.gov/pubmed/32046535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1176/appi.ajp.2019.19060583
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