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5-Formylcytosine landscapes of human preimplantation embryos at single-cell resolution

Epigenetic dynamics, such as DNA methylation and chromatin accessibility, have been extensively explored in human preimplantation embryos. However, the active demethylation process during this crucial period remains largely unexplored. In this study, we use single-cell chemical-labeling-enabled C-to...

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Bibliografische gegevens
Gepubliceerd in:PLoS Biol
Hoofdauteurs: Gao, Yun, Li, Lin, Yuan, Peng, Zhai, Fan, Ren, Yixin, Yan, Liying, Li, Rong, Lian, Ying, Zhu, Xiaohui, Wu, Xinglong, Kee, Kehkooi, Wen, Lu, Qiao, Jie, Tang, Fuchou
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7419013/
https://ncbi.nlm.nih.gov/pubmed/32730243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000799
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