Discovery and validation of surface N-glycoproteins in MM cell lines and patient samples uncovers immunotherapy targets

BACKGROUND: Multiple myeloma (MM) is characterized by clonal expansion of malignant plasma cells in the bone marrow. While recent advances in treatment for MM have improved patient outcomes, the 5-year survival rate remains ~50%. A better understanding of the MM cell surface proteome could facilitat...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Oldham, Robyn A A, Faber, Mary L, Keppel, Theodore R, Buchberger, Amanda R, Waas, Matthew, Hari, Parameswaran, Gundry, Rebekah L, Medin, Jeffrey A
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Immunotherapy Biomarkers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7418848/
https://ncbi.nlm.nih.gov/pubmed/32771993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000915
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