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ContamLD: estimation of ancient nuclear DNA contamination using breakdown of linkage disequilibrium
We report a method called ContamLD for estimating autosomal ancient DNA (aDNA) contamination by measuring the breakdown of linkage disequilibrium in a sequenced individual due to the introduction of contaminant DNA. ContamLD leverages the idea that contaminants should have haplotypes uncorrelated to...
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| Publicado no: | Genome Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7418405/ https://ncbi.nlm.nih.gov/pubmed/32778142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02111-2 |
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