Microglial burden, activation and dystrophy patterns in frontotemporal lobar degeneration

BACKGROUND: Microglial dysfunction is implicated in frontotemporal lobar degeneration (FTLD). Although studies have reported excessive microglial activation or senescence (dystrophy) in Alzheimer’s disease (AD), few have explored this in FTLD. We examined regional patterns of microglial burden, acti...

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Gepubliceerd in:J Neuroinflammation
Hoofdauteurs: Woollacott, Ione O. C., Toomey, Christina E., Strand, Catherine, Courtney, Robert, Benson, Bridget C., Rohrer, Jonathan D., Lashley, Tammaryn
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2020
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7418403/
https://ncbi.nlm.nih.gov/pubmed/32778130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01907-0
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