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Distinct and overlapping roles of STAG1 and STAG2 in cohesin localization and gene expression in embryonic stem cells

BACKGROUND: The three-dimensional organization of the genome in the nucleus plays an integral role in many biological processes, including gene expression. The genome is folded into DNA loops that bring together distal regulatory elements and genes. Cohesin, a ring-shaped protein complex, is a major...

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Detalhes bibliográficos
Publicado no:Epigenetics Chromatin
Main Authors: Arruda, Nicole L., Carico, Zachary M., Justice, Megan, Liu, Ying Frances, Zhou, Junjie, Stefan, Holden C., Dowen, Jill M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7418333/
https://ncbi.nlm.nih.gov/pubmed/32778134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-020-00353-9
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