Inhibition of p66Shc Oxidative Signaling via CA-Induced Upregulation of miR-203a-3p Alleviates Liver Fibrosis Progression

We previously found that inhibition of p66Shc confers protection against hepatic stellate cell (HSC) activation during liver fibrosis. However, the effect of p66Shc on HSC proliferation, as well as the mechanism by which p66Shc is modulated, remains unknown. Here, we elucidated the effect of p66Shc...

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Publicat a:Mol Ther Nucleic Acids
Autors principals: Wang, Zhecheng, Zhao, Yan, Zhao, Huanyu, Zhou, Junjun, Feng, Dongcheng, Tang, Fan, Li, Yang, Lv, Li, Chen, Zhao, Ma, Xiaodong, Tian, Xiaofeng, Yao, Jihong
Format: Artigo
Idioma:Inglês
Publicat: American Society of Gene & Cell Therapy 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417942/
https://ncbi.nlm.nih.gov/pubmed/32781430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.07.013
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