Synthesis and Biological Evaluation of Thio-Derivatives of 2-Hydroxy-1,4-Naphthoquinone (Lawsone) as Novel Antiplatelet Agents

We designed and synthesized in water, using conventional heating and microwave irradiation, new thio-derivatives of 2-hydroxy-1,4-naphthoquinone, a naturally occurring pigment known as lawsone or hennotannic acid, thus improving their antiplatelet activity with relevance to their potential future us...

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Bibliographic Details
Published in:Front Chem
Main Authors: Monroy-Cárdenas, Matías, Méndez, Diego, Trostchansky, Andrés, Martínez-Cifuentes, Maximiliano, Araya-Maturana, Ramiro, Fuentes, Eduardo
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Chemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417813/
https://ncbi.nlm.nih.gov/pubmed/32850615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2020.00533
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