In vitro Activity of Robenidine Analog NCL195 in Combination With Outer Membrane Permeabilizers Against Gram-Negative Bacterial Pathogens and Impact on Systemic Gram-Positive Bacterial Infection in Mice

Multidrug-resistant (MDR) pathogens, particularly the ESKAPE group (Enterococcus faecalis/faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Escherichia coli, and Enterobacter spp.), have become a public health threat worldwide. Development of new...

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Bibliographic Details
Published in:Front Microbiol
Main Authors: Pi, Hongfei, Nguyen, Hang Thi, Venter, Henrietta, Boileau, Alexandra R., Woolford, Lucy, Garg, Sanjay, Page, Stephen W., Russell, Cecilia C., Baker, Jennifer R., McCluskey, Adam, O’Donovan, Lisa A., Trott, Darren J., Ogunniyi, Abiodun D.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417630/
https://ncbi.nlm.nih.gov/pubmed/32849325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.01556
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