Pharmacokinetics of Pimobendan and Its Metabolite O-Desmethyl-Pimobendan Following Rectal Administration to Healthy Dogs

Objective: This study describes the pharmacokinetics of parent pimobendan (PIM) and its active metabolite, o-desmethyl-pimobendan (ODMP), after oral and rectal administration of pimobendan to healthy dogs. Animals: A total of eight healthy privately owned dogs were used in this study. Procedures: Th...

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Dettagli Bibliografici
Pubblicato in:Front Vet Sci
Autori principali: Her, Jiwoong, Kuo, Kendon W., Winter, Randolph L., Cruz-Espindola, Crisanta, Bacek, Lenore M., Boothe, Dawn M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Veterinary Science
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417621/
https://ncbi.nlm.nih.gov/pubmed/32851013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fvets.2020.00423
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