Antibacterial and Cytotoxic Bridged and Ring Cleavage Angucyclinones From a Marine Streptomyces sp

Chemical investigation of a marine-derived Streptomyces sp. KCB-132, cultivated in liquid ISP2 medium, had led to the discovery of three C-ring cleavage angucyclinone N-heterocycles, pratensilins A–C, with a novel spiro indolinone-naphthofuran skeleton. Addition of 50 μM LaCl(3) to the same medium a...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Guo, Lin, Zhang, Lu, Yang, Qiaoli, Xu, Bo, Fu, Xinzhen, Liu, Ming, Li, Zhi, Zhang, Shumin, Xie, Zeping
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417440/
https://ncbi.nlm.nih.gov/pubmed/32850626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2020.00586
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