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Population pharmacokinetics–pharmacodynamics of sunitinib in pediatric patients with solid tumors

PURPOSE: The safety profile of sunitinib in children, including the impact of sunitinib exposure on safety endpoints, was assessed using population pharmacokinetic (PK) and pharmacokinetic–pharmacodynamic (PK–PD) models. METHODS: Data were from two clinical studies in 59 children with solid tumors (...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Chemother Pharmacol
Egile Nagusiak: Wang, Erjian, DuBois, Steven G., Wetmore, Cynthia, Khosravan, Reza
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer Berlin Heidelberg 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417410/
https://ncbi.nlm.nih.gov/pubmed/32623479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-020-04106-z
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