Blockade of XCL1/Lymphotactin Ameliorates Severity of Periprosthetic Osteolysis Triggered by Polyethylene-Particles

Periprosthetic osteolysis induced by orthopedic implant-wear particles continues to be the leading cause of arthroplasty failure in majority of patients. Release of the wear debris results in a chronic local inflammatory response typified by the recruitment of immune cells, including macrophages. Th...

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Pubblicato in:Front Immunol
Autori principali: Tian, Yuan, Terkawi, Mohamad Alaa, Onodera, Tomohiro, Alhasan, Hend, Matsumae, Gen, Takahashi, Daisuke, Hamasaki, Masanari, Ebata, Taku, Aly, Mahmoud Khamis, Kida, Hiroaki, Shimizu, Tomohiro, Uetsuki, Keita, Kadoya, Ken, Iwasaki, Norimasa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417302/
https://ncbi.nlm.nih.gov/pubmed/32849609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01720
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