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Concentration-dependent mortality of chloroquine in overdose

Hydroxychloroquine and chloroquine are used extensively in malaria and rheumatological conditions, and now in COVID-19 prevention and treatment. Although generally safe they are potentially lethal in overdose. In-vitro data suggest that high concentrations and thus high doses are needed for COVID-19...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Watson, James A, Tarning, Joel, Hoglund, Richard M, Baud, Frederic J, Megarbane, Bruno, Clemessy, Jean-Luc, White, Nicholas J
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7417172/
https://ncbi.nlm.nih.gov/pubmed/32639233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58631
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