Heparan sulfate inhibits transforming growth factor β signaling and functions in cis and in trans to regulate prostate stem/progenitor cell activities

Prostate stem/progenitor cells (PrSCs) are responsible for adult prostate tissue homeostasis and regeneration. However, the related regulatory mechanisms are not completely understood. In this study, we examined the role of heparan sulfate (HS) in PrSC self-renewal and prostate regeneration. Using a...

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Bibliographic Details
Published in:Glycobiology
Main Authors: Rai, Sumit, Alsaidan, Omar Awad, Yang, Hua, Cai, Houjian, Wang, Lianchun
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Developmental Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7416765/
https://ncbi.nlm.nih.gov/pubmed/31829419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwz103
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