Population Pharmacokinetics of Intravenous Phenobarbital in Neonates after Congenital Heart Surgery

OBJECTIVES: To develop a population pharmacokinetic (PK) model for intravenous phenobarbital in neonates following cardiac surgery and perform simulations to identify optimal dosing regimens. DESIGN: Retrospective single-center PK study. SETTING: Cardiac Intensive Care Unit at Children’s Hospital of...

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Udgivet i:Pediatr Crit Care Med
Main Authors: Thibault, Céline, Massey, Shavonne L., Naim, Maryam Y., Abend, Nicholas S., Zuppa, Athena F.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7416482/
https://ncbi.nlm.nih.gov/pubmed/32224827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PCC.0000000000002341
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