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The SK Channel Inhibitors NS8593 and UCL1684 Prevent the Development of Atrial Fibrillation via Atrial-selective Inhibition of Sodium Channel Activity

The mechanisms underlying atrial-selective prolongation of effective refractory period (ERP) and suppression of atrial fibrillation (AF) by NS8593 and UCL1684, small conductance calcium-activated potassium (SK) channel blockers, are poorly defined. The purpose of the study was to confirm the effecti...

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Detalhes bibliográficos
Publicado no:J Cardiovasc Pharmacol
Main Authors: Burashnikov, Alexander, Barajas-Martinez, Hector, Hu, Dan, Robinson, Victoria M., Grunnet, Morten, Antzelevitch, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7416459/
https://ncbi.nlm.nih.gov/pubmed/32453071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0000000000000855
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