Apatinib induces apoptosis and autophagy via the PI3K/AKT/mTOR and MAPK/ERK signaling pathways in neuroblastoma

The clinical outcome of neuroblastoma (NB) has significantly improved in the last 30 years for patients with localized disease; however, the overall survival (OS) for patients with metastasis remains poor. Apatinib, a selective inhibitor of the vascular endothelial growth factor receptor-2 (VEGFR-2)...

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Bibliographic Details
Published in:Oncol Lett
Main Authors: Yu, Xiying, Fan, Hongjun, Jiang, Xingran, Zheng, Wei, Yang, Yanan, Jin, Mei, Ma, Xiaoli, Jiang, Wei
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2020
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7416412/
https://ncbi.nlm.nih.gov/pubmed/32788939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2020.11913
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