Enzymatic and Chemical-Based Methods to Inactivate Endogenous Blood Ribonucleases for Nucleic Acid Diagnostics

There are ongoing research efforts into simple and low-cost point-of-care nucleic acid amplification tests (NATs) addressing widespread diagnostic needs in resource-limited clinical settings. Nucleic acid testing for RNA targets in blood specimens typically requires sample preparation that inactivat...

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Udgivet i:J Mol Diagn
Main Authors: Bender, Andrew T., Sullivan, Benjamin P., Lillis, Lorraine, Posner, Jonathan D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7416074/
https://ncbi.nlm.nih.gov/pubmed/32450280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2020.04.211
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