Discovery and mechanistic studies of cytotoxic cyclotides from the medicinal herb Hybanthus enneaspermus

Cyclotides are plant-derived peptides characterized by an ∼30-amino acid–long cyclic backbone and a cystine knot motif. Cyclotides have diverse bioactivities, and their cytotoxicity has attracted significant attention for its potential anticancer applications. Hybanthus enneaspermus (Linn) F. Muell...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Chan, Lai Y., Gilding, Edward K., Henriques, Sónia Troeira, Condon, Nicholas D., Ravipati, Anjaneya S., Kaas, Quentin, Huang, Yen-Hua, Craik, David J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2020
Gaiak:
Protein Structure and Folding
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415973/
https://ncbi.nlm.nih.gov/pubmed/32414842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012627
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