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Exosomes derived from GDNF-modified human adipose mesenchymal stem cells ameliorate peritubular capillary loss in tubulointerstitial fibrosis by activating the SIRT1/eNOS signaling pathway

Mesenchymal stem cells (MSCs) have emerged as ideal cell-based therapeutic candidates for the structural and functional restoration of the diseased kidney. Glial cell line-derived neurotrophic factor (GDNF) has been demonstrated to promote the therapeutic effect of MSCs on ameliorating renal injury....

詳細記述

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書誌詳細
出版年:Theranostics
主要な著者: Chen, Lu, Wang, Yanping, Li, Shulin, Zuo, Bangjie, Zhang, Xiangyu, Wang, Fengzhen, Sun, Dong
フォーマット: Artigo
言語:Inglês
出版事項: Ivyspring International Publisher 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415791/
https://ncbi.nlm.nih.gov/pubmed/32802201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.43315
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