Perfluorooctanoic acid (PFOA), perfluorooctane sulfonic acid (PFOS), and perfluorononanoic acid (PFNA) increase triglyceride levels and decrease cholesterogenic gene expression in human HepaRG liver cells

Per- and polyfluoroalkyl substances (PFASs) are omnipresent in the environment, food chain, and humans. Epidemiological studies have shown a positive association between serum levels of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS), and increased serum cholesterol and, in so...

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Detalles Bibliográficos
Publicado en:Arch Toxicol
Main Authors: Louisse, Jochem, Rijkers, Deborah, Stoopen, Geert, Janssen, Aafke, Staats, Martijn, Hoogenboom, Ron, Kersten, Sander, Peijnenburg, Ad
Formato: Artigo
Idioma:Inglês
Publicado: Springer Berlin Heidelberg 2020
Assuntos:
Molecular Toxicology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415755/
https://ncbi.nlm.nih.gov/pubmed/32588087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-020-02808-0
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