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Exposure to smoke from high- but not low-nicotine cigarettes leads to signs of dependence in male rats and potentiates the effects of nicotine in female rats

Nicotine is only mildly rewarding, but after becoming dependent, it is difficult to quit smoking. The goal of these studies was to determine if low-nicotine cigarettes are less likely to cause dependence and enhance the reinforcing effects of nicotine than regular high-nicotine cigarettes. Male and...

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Detalhes bibliográficos
Publicado no:Pharmacol Biochem Behav
Main Authors: Chellian, Ranjithkumar, Behnood-Rod, Azin, Wilson, Ryann, Wilks, Isaac, Knight, Parker, Febo, Marcelo, Bruijnzeel, Adriaan W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415730/
https://ncbi.nlm.nih.gov/pubmed/32681850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2020.172998
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