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Fluconazole Analogues with Metal-Binding Motifs Impact Metal-Dependent Processes and Demonstrate Antifungal Activity in Candida albicans

Azole antifungals are an important class of antifungal drugs due to their low cost, ability to be administered orally, and broad-spectrum activity. However, their widespread and long-term use have given rise to adaptation mechanisms that render these compounds less effective against common fungal pa...

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Detalhes bibliográficos
Publicado no:J Biol Inorg Chem
Main Authors: Hunsaker, Elizabeth W., McAuliffe, Katherine J., Franz, Katherine J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415656/
https://ncbi.nlm.nih.gov/pubmed/32542530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-020-01796-x
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