Chromosome 6p amplification in aqueous humor cell-free DNA is a prognostic biomarker for retinoblastoma ocular survival

Aqueous humor (AH) contains tumor-derived cell-free DNA (cfDNA) and can serve as a liquid biopsy for retinoblastoma (RB). We previously associated somatic copy number alteration (SCNA) 6p gain with a 10-fold increased risk of enucleation. Here we provide a 2-year update to further explore 6p gain as...

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Publicado en:Mol Cancer Res
Main Authors: Xu, Liya, Polski, Ashley, Prabakar, Rishvanth K., Reid, Mark W., Chevez-Barrios, Patricia, Jubran, Rima, Kim, Jonathan W., Kuhn, Peter, Cobrinik, David, Hicks, James, Berry, Jesse L.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415535/
https://ncbi.nlm.nih.gov/pubmed/32434859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-19-1262
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