Metformin suppresses inflammation and apoptosis of myocardiocytes by inhibiting autophagy in a model of ischemia-reperfusion injury

Metformin (Met) is a major widely used oral glucose lowering drug for the treatment of type 2 diabetes. It is reported that metformin could regulate autophagy in various diseases of cardiovascular system including in I/R injury, diabetic cardiomyopathy and heart failure. Autophagy plays a controvers...

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Vydáno v:Int J Biol Sci
Hlavní autoři: Huang, Kai-yu, Que, Jia-qun, Hu, Ze-song, Yu, Yong-wei, Zhou, Ying-ying, Wang, Lei, Xue, Yang-jing, Ji, Kang-ting, Zhang, Xin-min
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2020
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415420/
https://ncbi.nlm.nih.gov/pubmed/32792857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.40823
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