Elimination of a Retinal Riboflavin Binding Protein Exacerbates Degeneration in a Model of Cone-Rod Dystrophy

PURPOSE: Riboflavin and its cofactors are essential for cellular energy generation, responses to oxidative stress, and overall homeostasis. Retbindin is a novel retina-specific riboflavin binding protein essential for the maintenance of retinal flavin levels, but its function remains poorly understo...

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Bibliographic Details
Published in:Invest Ophthalmol Vis Sci
Main Authors: Genc, Ayse M., Makia, Mustafa S., Sinha, Tirthankar, Conley, Shannon M., Al-Ubaidi, Muayyad R., Naash, Muna I.
Format: Artigo
Language:Inglês
Published: The Association for Research in Vision and Ophthalmology 2020
Subjects:
Biochemistry and Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415289/
https://ncbi.nlm.nih.gov/pubmed/32516403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.6.17
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