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Role of Toxin-Antitoxin-Regulated Persister Population and Indole in Bacterial Heat Tolerance

YafQ is an endoribonuclease toxin that degrades target gene transcripts such as that of tnaA, a gene encoding tryptophanase to synthesize indole from tryptophan. DinJ is the cognate antitoxin of YafQ, and the YafQ-DinJ system was reported to regulate persister formation by controlling indole product...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Main Authors: Masuda, Yoshimitsu, Sakamoto, Erika, Honjoh, Ken-ichi, Miyamoto, Takahisa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414958/
https://ncbi.nlm.nih.gov/pubmed/32503909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00935-20
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