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Bioequivalence Study of Amitriptyline Hydrochloride Tablets in Healthy Chinese Volunteers Under Fasting and Fed Conditions

PURPOSE: This study compares the pharmacokinetic and safety profiles between a new generic and a branded reference formulation of amitriptyline hydrochloride tablets, and assesses the bioequivalence of the two products in healthy Chinese volunteers to obtain sufficient evidence for the marketing app...

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Bibliografske podrobnosti
izdano v:Drug Des Devel Ther
Main Authors: Zhai, You, Wu, Lihua, Zheng, Yunliang, Wu, Minglan, Huang, Yujie, Huang, Qian, Shentu, Jianzhong, Zhao, Qingwei, Liu, Jian
Format: Artigo
Jezik:Inglês
Izdano: Dove 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414938/
https://ncbi.nlm.nih.gov/pubmed/32801649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S258173
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