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Development and validation of a 1-year survival prognosis estimation model for Amyotrophic Lateral Sclerosis using manifold learning algorithm UMAP

Amyotrophic Lateral Sclerosis (ALS) is an inexorably progressive neurodegenerative condition with no effective disease modifying therapies. The development and validation of reliable prognostic models is a recognised research priority. We present a prognostic model for survival in ALS where result u...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Grollemund, Vincent, Chat, Gaétan Le, Secchi-Buhour, Marie-Sonia, Delbot, François, Pradat-Peyre, Jean-François, Bede, Peter, Pradat, Pierre-François
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414917/
https://ncbi.nlm.nih.gov/pubmed/32770027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70125-8
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