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Using whole-genome sequencing data to derive the homologous recombination deficiency scores
The homologous recombination deficiency (HRD) score was developed using whole-genome copy number data derived from arrays as a way to infer deficiency in the homologous recombination DNA damage repair pathway (in particular BRCA1 or BRCA2 deficiency) in breast cancer samples. The score has utility i...
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| Vydáno v: | NPJ Breast Cancer |
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| Hlavní autoři: | , , , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7414867/ https://ncbi.nlm.nih.gov/pubmed/32818150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41523-020-0172-0 |
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